The day a woman gets her period marks the beginning of her reproductive years up until menopause. Many women will begin to undergo age-related changes in their body, like uterine fibroids, which are often asymptomatic non-cancerous tumors that grow within the wall of the uterus. The size, number, and location of the fibroids could determine the extent of complications a woman may face.
So, who's at risk for fibroids?
The majority of women will have uterine fibroids: 70 to 80 percent of women will have uterine fibroids before the age of 50, though there are differences in expectation about when they may turn up.
Dr. Wendy Chang, a reproductive endocrinologist and OB GYN at the Southern California Reproductive Center in California, says fibroids are largely seen during the reproductive years (20s to 50s), and often shrink during menopause.
However, "fibroids have not been observed in prepubertal girls, but have been seen in adolescents", she told Medical Daily .
Fibroid risk includes early onset of menstruation, with prevalence for fibroids increasing with age, specifically during each decade of life before menopause. In addition, Chang explains, race also influences susceptibility, with black women two to three times more likely than white women to get the benign tumors.
Types Of Fibroids
Fibroid symptoms only occur in a minority of women, and what type they get can vary by individual. There are three types of fibroids that can turn up within the uterus, including the submucosal (the inner part of the uterus), subserosal (protruding out of the uterus onto the bladder), and intramural (in the wall of the uterus). There are other fibroids, known as pedunculated, which develop a stem (a slender base that supports the tumor.
It's not clear what causes fibroids, but there are several factors that may influence their formation. Therefore, no one knows what causes them to grow or shrink. However, it is known they're under hormonal control, both estrogen and progesterone. They tend to grow rapidly during pregnancy, when hormone levels are high, but they shrink when anti-hormone medication is used. Fibroids stop growing or shrinking once a woman reaches menopause.
Fibroids aren't as scary as they sound, but it's important to be aware of these 6 common symptoms.
A "Tiny" Bladder
The urge to pee very frequently could be a sign fibroids are growing on the outside of the uterus, protruding out into the abdomen. Women who tend to get up in the middle of the night to urinate, tend to urinate small amounts, or have difficulty initiating urination, could have fibroids.
According to Chang, this is due to the fibroids pressing into its neighbor, the bladder, which results in pressure, urgency at low bladder volumes, frequency or other bladder symptoms.
Constipation
There are fibroids that grow anteriorly — at the front of the uterus — that they push against the rectum. can interfere with bodily secretions.
Moreover, Chang notes: "Large fibroids that grow posteriorly (to the back), can press into the rectum and can sometimes impact bowley movement quality or frequency".
The pressure on the bowel can lead to constipation or bloating, or both.
Abdominal Fullness
Fibroids can lead to noticeable swelling in the lower abdomen, which could make a women appear pregnant. This may be due to the size of some fibroids that could appear physically obvious in the abdominal cavity. Women who do experience abdominal fullness should seek immediate medical attention.
Heavy Menstrual Bleeding
A heavy period is the most common symptom of fibroids for women.
"Fibroids, especially those that distort or grow into the uterine lining, often contribute to heavier menses", said Chang.
Those lodged in the wall of the uterus can cause heavy bleeding, leading to heavier periods. Moreover, fibroids may change the shape of the uterus. For women who report heavy menses, Chang suggests getting an ultrasound to reveal if fibroids is the causation of excessive menstrual bleeding.
Fibroids can also lead to longer periods, but it's not known why.
Lower Back Pain
If fibroids are large enough, they may cause enough pressure to create muscular or spinal pain. A small fibroid within the uterine wall is less likely to cause back pain.
"Rarely, fibroids may compress or exert mass effect near the sacral nerves," said Chang.
However, she warns this is very rare, not common at all, and other causes of low back pain should be ruled out.
Painful Sex
Pressure on the uterus, whether inside or out, or growths in or around the cervix can lead to pain. It is little controversial whether women with fibroids in any location are more likely to experience painful sex, compared to those without, according to Chang.
Among women with fibroids and painful sex, "anterior or fundal (at the top) fibroids are the more likely to be associated" she said.
If you experience any of these symptoms, it doesn't mean you have fibroids. They could also be an sign of various health conditions. It's best to talk to your doctor to get an abdominal or pelvic exam, an ultrasound or an MRI to confirm the diagnosis.
Posted via Blogaway
Friday, 23 December 2016
6 Signs You May Have A Fibroid Tumor Within Your Uterus
Thursday, 22 December 2016
HIV - Return of a Pandemic
Researchers reject vitamin D role in macular degeneration
WARNING! 6 tests to help you spot fake rice..
Reports indicate that China produces fake rice which is mixed with plastic for exportation to African countries including Nigeria.
China has a history of making fake food items and the fake rice phenomenon has been there for a while.
A reputable English-language newspaper in Korea, The Korea Times, reported that “ China famous for having all, making all, has now been reported to have made rice out of plastic and has distributed it. ”
The ‘plastic rice’ is reportedly made by forming potatoes and sweet potatoes into regular rice grains shape, then adding industrial synthetic resins. It remains hard after cooking and can cause serious health issues.
Experts have raised the alarm of possible flooding of the Nigerian market with the ‘plastic rice’.
As Christmas draws close, a lot of people will be getting bags of rice from their employers, friends and well-wishers.
You can determine if your rice is fake by carrying out any of the simple tests below.
1. The mortar and pestle test
When molding a few grains of rice with a mortar and pestle, if the powder gives a quite white colour, you are good to go but it has a yellow discoloration, your rice must be fake.
2. The fire test
You know what plastic smells like right. So, get a lighter and burn a handful of rice. If it catches fire and smells like burnt plastic, you have fake rice.
3. The water test
Get a glass of cold water. Pour a tablespoon of raw rice in the glass and stir. If the rice goes to the bottom, it is all good. If it floats at the top, be careful because it means it contains ‘plastic rice’. Do not eat.
4. The mold test
Boil the rice. Leave it in a warm place for like 2-3 days. If mold does not appear in a few days, your rice is fake and should not be consumed. It will not get mold because plastic is not affected by the weather or temperature.
5. The boiling test
Observe the rice while boiling. If it starts forming a thick layer at the top of the pot, it is ‘plastic rice’.
6. The hot oil test
Just take some of the rice drop into some real hot oil. If it is plastic, it will melt or stick together or stick at the bottom of the pan.
Share these tips with your friends and family so they do not end up eating ‘plastic rice’. These tests are very simple. Do not eat plastic rice, be careful.
Posted via Blogaway
Wednesday, 21 December 2016
Benefits Of Nuts: Eating 10 Grams Of Nuts And Peanuts A Day Lowers Death Risk Of Major Causes
Eating tree nuts and peanuts is a good way to eat enough protein, stay fit, and protect yourself from chronic diseases.
Eating nuts has been associated with plenty of health benefits — from increased cognitive function to protection from Alzheimer's, as well as keeping your heart healthy. Now, scientists have added more benefits to that list: People who eat a lot of nuts might have a lower risk of mortality and developing chronic diseases, including respiratory disease, neurodegenerative disease, diabetes, cancer, and heart disease, according to a new published in the International Journal of Epidemiology.
In the study, researchers examined data from the Netherlands Cohort Study, which includes information about 120,000 Dutch 55- to 69-year-old men and women from 1986 to the present day. They measured nut intake by asking about portion size and the frequency at which the participants ate tree nuts, peanuts, and peanut butter.
“It was remarkable that substantially lower mortality was already observed at consumption levels of 15 grams of nuts or peanuts on average per day (half a handful),” Professor Piet van den Brandt, the project leader and epidemiologist, said in the study . “A higher intake was not associated with further reduction in mortality risk. This was also supported by a meta-analysis of previously published studies together with the Netherlands Cohort Study, in which cancer and respiratory mortality showed this same dose-response pattern.”
It turns out that eating pure peanuts instead of peanut butter is better: The researchers found no improvement press release people who ate peanut butter, which typically contains non-healthy additives like salt and vegetable oils. But in those who ate peanuts, their mortality risk was lowered.
It’s been known for some time that nuts — which are rich in essential nutrients like fiber, protein, minerals, monounsaturated and polyunsaturated fatty acids, and antioxidants — have plenty of health benefits. One 2010 study notes that “by virtue of their unique composition, nuts are likely to beneficially impact health outcomes. Epidemiologic studies have associated nut consumption with a reduced incidence of coronary heart disease and gallstones in both genders and diabetes in women,” and “studies consistently show that nut intake has a cholesterol-lowering effect.”
But the new study is really the first to show that those benefits are so wide-ranging and encompassing — and can extend past study health and helping people manage weight/diabetes.
Source: Brandt P, Schouten L. Relationship of tree nut, peanut, and peanut butter intake with total and cause-specific mortality: a cohort study and meta analysis. International Journal of Epidemiology. 2015.
Is Garlic Good For You? 7 Surprising Benefits Of Garlic For Optimal Health
Garlic does more than just invigorate your palate and ward off vampires; it’s also a smelly superfood health aid. The spice is a highly nutritious vegetable with very few calories, containing trace amounts of other nutrients that contribute to its universal status of a powerful, beneficial healer. The natural medicinal ingredient, both as a fresh plant and supplement, can strengthen immune function and boost overall well-being.
Garlic’s delicious flavor and health benefits have led to a steady increase in demand. The average garlic consumption per capita per year is 2 pounds. A healthy adult can safely consume up to four cloves of garlic each day, according to the University of Maryland Medical Center, with each one weighing about a gram.
The body-strengthening effects of this herb are thought to be due to its active ingredient allicin. This is what gives garlic its distinctive taste and smell. Whether you take your garlic powdered, salted, minced or in supplement form, you can reap the surprising benefits of this multipurpose herb for optimal health.
1. TREATS ACNE
This herb may not be found in acne products’ list of ingredients, but it can serve as a natural topical treatment to get rid of blemishes. Allicin, the organic compound in garlic, has the ability to stop the damaging effects of radicals and kill bacteria, according to a 2009 study published in the journal Angewandte Chemie. In its decomposed form — sulfenic acid — allicin produces a fast reaction with radicals, which makes it a valuable herb for treating acne scars, skin diseases, and allergies.
2. TREATS HAIR LOSS
A head full of hair that smells like garlic could help in the treatment of hair loss. The herb’s extremely high sulfur content contains keratin, the protein hair is made of. This stimulates fortification and growth. A 2007 study published in the Indian Journal of Dermatology, Venerology and Leprology found the use of a garlic gel added to the therapeutic efficacy of topical betamethasone valerate for alopecia areata treatment can be effective to induce hair re-growth.
3. FIGHTS COMMON COLD
Garlic’s allicin can serve as a health aid during times of illness. Rene Fisek, a registered dietician and a lead nutrition expert at Seattle Sutton's Healthy Eating in Illinois told Medical Daily in an email: “Garlic cloves contain a healthy dose of allicin, but you may still need a few cloves per day to feel the effects.” However, garlic supplementation can also be used to ward off viruses.
A 2001 published in the journalAdvances In Therapy found a daily garlic supplement can reduce the number of colds by 63 percent compared to not taking supplements. Moreover, the average length of cold symptoms was also reduced to 70 percent, from five days in the control group to 1.5 days in garlic study group. These findings suggest the allicin-containing supplement has a protective effect against the common cold.
4. LOWERS BLOOD PRESSURE
A garlic supplement a day may help keep your blood pressure at bay. Its active compounds can significantly reduce blood pressure comparable to the effects of prescribed drugs. Aged garlic extract between 600 to 1,500 milligrams (mg) was found to be just as effective as the drug Atenolol prescribed for hypertension in a 24-week period, according to a 2013 study published in the Pakistan Journal of Pharmaceutical Sciences.
Garlic is believed to activate the production of the endothelium-derived relaxation factor, according to Ficek, due to the herb’s high amount of polysulfides — sulfur — containing molecules. This leads to smooth muscle relaxation and vasodilation (widening of blood vessels), following the relaxation of the smooth muscle in the vessel wall. Garlic supplements can achieve these effects efficiently without the bad breath compared to raw garlic.
5. LOWERS HEART DISEASE RISK
Garlic can help lower the risk of heart disease by lowering total LDL cholesterol. A 2000 study published in the journal Annals of Internal Medicine found the effect of garlic on total cholesterol level in people with elevated levels moderately reduced cholesterol levels. Vandana Sheth, registered dietitian nutritionist and spokesperson for the Academy of Nutrition and Dietetics told Medical Daily in an email that this is achieved by “diminishing the activity of main cholesterol-producing enzyme in the liver.” Garlic supplements can enhance the body’s ability to dissolve blood clots that would otherwise increase the risk of heart attacks by closing the arteries.
6. ENHANCES PHYSICAL PERFORMANCE
Garlic can help increase exercise capacity and reduce exercise-induced fatigue. “[G]arlic has a long history of being used in ancient cultures to reduce fatigue and enhance the work capacity of laborers,” Ficek said. Garlic oil has been shown to improve the exercise capacity of people with heart disease. A 2005 study published in the Indian Journal of Physiology and Pharmacology found participants with heart disease who took garlic oil for six weeks saw a reduction in peak heart rate by 12 percent. This was accompanied by an improvement in their physical endurance during a treadmill exercise.
7. IMPROVES BONE HEALTH
The alkalizing vegetable is filled with bone-healthy nutrients such as zinc, manganese, vitamin B6, and vitamin C., a holistic nutritionist and ChazzLIVE expert told Medical Daily in an email: “Garlic is really high in manganese, which contains enzymes and antioxidants that facilitates the formation of bones and connective tissues, bone metabolism, and calcium absorption.”
Garlic may help reduce bone loss through the increase of estrogen in females. Risa Groux 2007 study published in the journal Phytotherapy Research found garlic oil was able to preserve the skeletal health of rodents when under a hypogonadal situation. In other words, garlic contains nutrients that act as building blocks for healthy, strong bones.
Garlic can be a flavorful addition to your dish and also double as a valuable aid to your health.
Tuesday, 20 December 2016
Prostate cancer laser treatment 'truly transformative'
MediaProfessor Mark Emberton explains on Radio 4's Today the significance of new cancer treatment
Surgeons have described a new treatment for early stage prostate cancer as "truly transformative".
The approach, tested across Europe, uses lasers and a drug made from deep sea bacteria to eliminate tumours, but without causing severe side effects.
Trials on 413 men - published in The Lancet Oncology - showed nearly half of them had no remaining trace of cancer.
Lifelong impotence and incontinence are often the price of treating prostate cancer with surgery or radiotherapy.
Up to nine- in - 10 patients develop erectile problems and up to a fifth struggle to control their bladders.
That is why many men with an early stage tumour choose to "wait and see" and have treatment only when it starts growing aggressively.
"This changes everything," said Prof Mark Emberton, who tested the technique at University College London.
Triggered to kill
The new treatment uses a drug, made from bacteria that live in the almost total darkness of the seafloor and which become toxic only when exposed to light.
Ten fibre optic lasers are inserted through the perineum - the gap between the anus and the testes - and into the cancerous prostate gland.
When the red laser is switched on, it activates the drug to kill the cancer and leaves the healthy prostate behind.
The trial - at 47 hospitals across Europe - showed 49% of patients went into complete remission.
And during the follow-up, only 6% of patients needed to have the prostate removed, compared with 30% of patients that did not have the new therapy.
Crucially, the impact on sexual activity and urination lasted no more than three months.
No men had significant side effects after two years.
Gerald Capon, 68 and from West Sussex, told the BBC: "I'm totally cured and free of the cancer.
"I feel incredibly lucky that I was accepted for the trial... I feel that my life ahead is worry free."
He was out of hospital the day after the treatment.
Prof Emberton said the technology could be as significant for men as the move from removing the whole breast to just the lump in women with breast cancer.
He said: "Traditionally the decision to have treatment has always been a balance of benefits and harms.
"The harms have always been the side effects - urinary incontinence and sexual difficulties in the majority of men.
"To have a new treatment now that we can administer, to men who are eligible, that is virtually free of those side effects, is truly transformative."
11,000 deaths
More than 46,000 men are diagnosed with prostate cancer in the UK each year.
The tumours tend to grow slowly, but still around 11,000 men die from the disease.
However, the new treatment is not yet available for patients. It will be assessed by regulators at the beginning of next year.
Other therapies to kill prostate cancers, such as very focused ultrasound - known as focal Hifu - have a lower risk of side effects.
But these treatments are not universally available.
Dr Matthew Hobbs, from the charity Prostate Cancer UK, said the technology could help men who face the conundrum of whether or not to have treatment.
"Focal therapy treatments like this one have the potential to offer a middle ground option for some men with cancer that has not spread outside the prostate," he said.
Caution urged
He said the next challenge would be to find out which patients should still wait and see, which ones should have this type of therapy, and which should have more invasive treatments.
"Until we know the answer to this question, it is important that these results do not lead to the over-treatment of men with low risk cancer, or the under treatment of men at higher risk."
The technology was developed at the Weizmann Institute of Science in Israel alongside Steba Biotech.
Source: BBC News
By James Gallagher
20 December, 2016
Woman Notices Strange Hump After Years Of Drinking, But Doctors Have Never Seen This Before
This is one medical phenomenon I thought I’d never see. Doctors were stunned when a 64-year-old woman developed lumps on her arms and torso… and also a massive growth on her back referred to as “buffalo hump.” The woman said she was aware of her worsening deformities for at least five years, but since they didn’t make her physically uncomfortable, she was okay with them. However, she was also suffering from progressive muscle weakness that become so severe she could barely leave her house. When she finally arrived at the Brooklyn Hospital Center, doctors noticed she was confused and disoriented. That’s when the woman admitted to being a heavy drinker for 40 years. Her last binge was about two weeks prior to her first hospital visit. Doctors sent her in for CT scans, but the mysterious lumps turned out to be non-cancerous. As a last resort, they searched the internet and diagnosed her with Madelung's disease, a rare illness typically seen among male alcoholics. Madelung’s causes fatty tumors called lipomas to form under the skin. Blood tests revealed the woman had ketoacidosis, a rare but dangerous condition typically seen in patients with type 1 diabetes. Decades of alcohol abuse also left her with fatty liver disease. Doctors gave the woman two solutions. She was advised to stop drinking alcohol, and they gave her the option to treat the hump on her back with liposuction. The woman decided to stop drinking, but did not opt for the liposuction.
Low-Carb Vs Low-Fat Diets: Which Is More Effective For Weight Loss?
Low-Carb Vs. Low-Fat Diets: Which Is More Effective For Weight Loss?
Trying to lose weight by avoiding foods with high amounts of fat? According to a new study from researchers at the Mayo Clinic in Arizona, low-carbohydrate diets could actually be more effective for shedding pounds.
The study showed low- carb diets have a slight advantage over low-fat diets in reducing weight. Researchers also found that diets where you limit carbohydrates are relatively safe in the short term, UPI reported.
To understand the overall safety and potential negative effects of certain diets, the research team analyzed data from January 2005 to April 2016. Findings showed that over a six-month period, people on low-carb diets lost between 2.5 and almost 9 pounds more than those on a low-fat diet.
Avoiding carbohydrates could be more effective for weight loss than avoiding fat.
In the short term, results showed no negative side effects on blood pressure, glucose and cholesterol, but the source or quality of the proteins and fats consumed on the examined low-carb diets were not disclosed.
Additionally, as researchers acknowledged, there are multiple variables when it comes to the amounts of carbohydrates in various low-carb diet plans.
"The best conclusion to draw is that adhering to a short-term low carb diet appears to be safe and may be associated with weight reduction. However, that weight loss is small and of questionable clinical significance in comparison to low fat diets, said Dr. Heather Fields, lead researcher on the study, according to UPI.
"We encourage patients to eat real food and avoid highly-processed foods, especially processed meats, such as bacon, sausage, deli meats, hot dogs and ham when following any particular diet," she added.
A previous study linked low-carbohydrate meals to healthy changes in a woman's metabolism, HealthDayreported earlier this month.
Source: Fields H, Ruddy B, Wallace MR, Shah A, Millstine D. Are Low-Carbohydrate Meals Safe And Effective?The Journal of the American Osteopathic Association 2016
5 Signs Your Headache Is Something More...
Most of the time, headaches are caused by hangovers, tension, or sinus problems during a weather change. But when headaches are sudden and debilitating, or accompanied by other worrisome red flags, it might mean there’s something worse going on. Here’s how to recognize five different symptoms that are more than just a headache so you can get the medical treatment you need.
MIGRAINES WITH AURAS
Migraines are different from regular headaches because they are usually much, much worse, and can be accompanied by nausea, vomiting, and severe sensitivity to light and sound. Some migraine sufferers experience auras before, during, or after their migraines; auras are visual sensations that can be manifested as shimmering lights, arcs, or shapes. Studies have shown that people who experience auras with their migraines have double the risk of stroke. If you suffer from aura migraines, be sure to cut back on smoking and other stroke risk factors.
If you're suffering from any of these types of headaches, see your doctor to get it checked out.
‘THUNDERCLAP’ HEADACHES
A “thunderclap” headache will typically involve a sudden, intense pain that peaks within 60 seconds, and fades over hours or even weeks. Thunderclap headaches are often described as being the “worst headache of my life” and can be a symptom of life-threatening problems like brain bleeding. Sometimes they’re accompanied by vomiting or losing consciousness, and can be caused by a lack of blood supply in the pituitary gland, blood clots, or a tear in an artery that leads to the brain. If you experience a thunderclap headache, seek medical help immediately.
MENINGITIS PAIN
If your headache comes with a stiff neck and muscle pain, as well as fever, vomiting, rashes and light sensitivity, you may be suffering from meningitis — a viral or bacterial infection of the meninges, or membranes surrounding the brain and spinal cord. If you have meningitis, you need to seek medical attention immediately as it can be a fatal disease.
BRAIN TUMOR HEADACHE
Some headaches are actually caused by brain tumors, though this is quite rare. According to the American Brain Tumor Association (ABTA), brain tumor headaches are often persistent and don’t respond to regular headache remedies like rest or medicine. They also might be worse after waking up in the morning, and be accompanied by vomiting or other neurological symptoms. Brain tumors can be diagnosed by an MRI, so be sure to visit the doctor if you think your headache is abnormal.
HEADACHES FOLLOWING INJURY
Headaches after a blow to the head might be a sign of a concussion or traumatic brain injury (TBI), which can be damaging over the long-term. After a TBI, headaches may occur when small pools of blood or fluid appear in the skull. TBI headaches are characterized by dull or throbbing sensations, nausea/vomiting, and even auras
Alzheimer's Diagnostic Test Developed by 15- Year Old Brit
Alzheimer's Diagnostic Test Developed By 15-Year-Old Brit May Both Diagnose And Prevent The Disease
A British school boy — who happens to be only 15 years old — has developed a new test with the potential to diagnose Alzheimer’s disease 10 years before the first symptoms appear. It may be able to halt the disease altogether.
Krtin Nithiyanandam, who hails from Epsom, Surrey, came up with his creation for the Google Science Fair, and has made it through to the final week. He'll find out next month whether he has won the grand prize, a prestigious scholarship and the opportunity to take his idea further.
The test consists of an antibody that can penetrate the brain and attach to neurotoxic proteins that appear during the first stages of the disease. The “Trojan horse” antibodies also attach to fluorescent particles that can be observed through a brain scan.
“The main benefits of my test are that it could be used to diagnose Alzheimer’s disease before symptoms start to show by focusing on pathophysiological changes, some of which can occur a decade before symptoms are prevalent,” Krtin told The Daily Telegraph. "This early diagnosis could help families prepare for the future and ensure that existing drugs are used to better effect."
Normally, neurodegenerative diseases like dementia are so difficult to diagnose and treat because of the blood-brain barrier, a highly exclusive permeability barrier that separates circulating blood from the brain. The barrier is highly selective, often only allowing water, some gases, and the specific molecules crucial to neural function to pass through. According to research, The blood-brain barrier blocks the entry of 100 percent of large-molecule neurotheraputics and 98 percent of all small-molecule drugs. Krtin’s antibodies, however, can pass through the barrier, allowing them to be much more useful than any previous attempts at early diagnosis of Alzheimer’s.
“Some of my new preliminary research has suggested that my diagnostic probe could simultaneously have therapeutic potential as well as diagnostic,” said Krtin, who attends Sutton Grammar School.
Lab tests showed that the antibodies had the capability to “handcuff” toxic proteins and stop them from developing further. This could potentially stop Alzheimer’s altogether.
Worldwide, almost 44 million people have Alzheimer’s or a related dementia. In the UK, 850,000 suffer from dementia, and the disease kills at least 60,000 people per year. In the U.S., Alzheimer’s is the only disease in the top 10 causes of death that cannot currently be prevented, cured, or even slowed.
"I chose Alzheimer’s disease because I am fascinated by neuroscience and the workings of the brain,” Krtin said. “I learned about its cruel and devastating effects and how it interferes with everyday life, and nobody should have to live with this debilitating disease."
Krtin suffered from auditory problems as a child, and hopes to study medicine when he leaves school.
“We want to support and foster the next generation of scientists and engineers,” Andrea Cohan, Google Science Fair’s Marketing Lead, told The Daily Telegraph. “The UK has once again proven itself as a hotbed of science creation.” Cohan said that young people often possess the creative ability to solve some of the world’s biggest challenges.
Krtin, who moved to the UK from India with his family as an infant, told The Daily Telegraph that winning the science fair would be “life changing.”
“It would be more than a dream come true, and it would also encourage me to pursue my interests in science, and hopefully one day, to change the world.
Monday, 19 December 2016
HIV Research Breakthroughs 2016: How close we've come to a cure, and better treatment
INNOVATION
HIV Research Breakthroughs 2016: How Close We've Come To A Cure, And Better Treatments
Human Immunodeficiency Virus, HIV, is a sexually transmitted virus that has infected millions around the globe. Although the virus is manageable with medication, people continue to die from HIV-related complications. Each year, we come a little closer to an eventual cure; here’s what research taught us about HIV in 2016.
REMOVING HIV FROM HUMAN DNA
Genetic editing is at the forefront of many medical advancements, including in HIV research. In a study published in March, researchers from Temple University succeeded in using a CRISPR/Cas9 gene editing technique to effectively edit out and eliminate the HIV virus from DNA in human cells.
What’s more, unlike past attempts to remove HIV from human DNA, this current study shows that edited cells are not susceptible to becoming reinfected again. The finding shows the effectiveness of gene editing tools on HIV, and suggest that one day these tools may even lead to a cure.
FIRST VACCINE AGAINST VIRUS GOES TO TRIAL IN SOUTH AFRICA
While a cure for HIV would be amazing, finding a vaccine to protect against the virus is also important. In July, trials of what may be the first HIV vaccine began in South Africa, an area of the world with the highest HIV infection rate, CNN reported. The trial, called HVTN 702, will run over the course of three years in South Africa, with 5,400 people across four sites receiving the experimental drug.
The vaccine works off of a previous vaccine attempt in 2009 which unfortunately was only 31 percent effective in preventing the disease. However, researchers are confident that improvements to the formula will make this vaccine more effective.
FURTHER IMPROVING ANTIVIRAL DRUGS
In a study published in August, scientists from the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge and University College London have discovered an essential feature of the HIV virus that it uses to infect cells while avoiding detection by the immune system, which may allow them to develop more effective drug treatments to control the virus.
Current drugs used to treat HIV are called antiretroviral treatment (ART). They work by keeping the level of HIV in your body low and allowing your immune system to stay strong, AVERT reported.
Friday, 16 December 2016
5 Best Kidney Cleansing Drinks You Should Try
The kidneys are one of the most important organ in the body. They act as filters for the blood to help remove impurities from the body, in the form of urine.
A good diet along with adequate hydration and regular intake of any of the kidney-friendly beverages below, will keep them working at their optimal levels.
Below are the 5 Best Kidney Cleansing Drinks You Should Try:
5 Best Kidney Cleansing Drinks You Should Try
1. Beet Juice
Beet juice has beneficial benefits for the urinary tract due to its betaine content. Betaine is a powerful antioxidant which, like cranberry juice, increases urine acidity, therefore inhibiting bacterial growth.
It also helps prevent build-up of struvite and calcium, which in turn helps reduce the risk of kidney stone formation.
2. Cranberry Juice
Cranberry juice is the most popular remedy for the urinary tract. This juice helps ward off the bacterial growth that leads to urinary tract infections. This happens by increasing the acidity of the urine, which makes if more difficult for bacteria to adhere to the urinary tract.
3. Juice Cleanses
Fruit and vegetable juice blends are highly effective way to cleanse the kidneys. This is because these juice blends are rich in antioxidants, minerals and vitamins, which help to detoxify the body and reduces the work load of the kidneys and liver.
Fruits such as apples, citrus, pears and peaches are perfect when combined with vegetables like cucumbers, kale and spinach.
4. Homemade Drinks
For the kidney cleansing drink you can make at home, combine drinking water, lemon juice, apple cider vinegar and a supplement called Renaltrex.
The ingredients in Renaltrex, helps to strengthen and detoxify the kidneys. This is essential in supporting overall renal health.
5. Lemon Juice
Regular consumption of lemon juice will help reduce the risk of developing kidney stones. It is highly acidic, which helps in dissolving stones and increases urinary citrate levels, which also fights stone formation.
For a quick and easy cleanse, take one quart of water and combine the juice of 4-5 lemons . You can drink it up after.
Thursday, 15 December 2016
Common Herpes Symptoms in Men
HERPES SYMPTOMS IN MEN:
Painful sores, swollen lymph nodes, and other common outbreak signs.
Genital herpes is one of the most common sexually transmitted infection in the United States, and according to the Centers for Disease Control and Prevention, around one in six people between the ages of 14 and 49 have genital herpes. The virus is often symptomless, or if you do have symptoms, they're easy to confuse with something else. Here is what men need to know about the virus.
WHAT IS HERPES?
Genital herpes is caused by two closely related viruses called herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). According to Young Men’s Health Site, HSV-1 infections may cause no symptoms, or cold sores and/or fever blisters on the lips. Although less common, HSV-1 can spread through oral sex, and can cause genital herpes.
On the other hand, HSV-2 is almost always spread by sexual contact. Symptoms of an HSV-2 infection can include painful lesions around the penis, and anus.
SYMPTOMS
Symptoms of genital herpes in men include small painful blisters around the penis that eventually break open and cause raw painful sores that can take weeks to completely heal. During the first outbreak, the sores are also associated with a fever, headache, flu-like symptoms, swollen lymph nodes, and muscle aches.
Genital herpes can be caused by either herpes simplex virus type 1 (HSV-1), or herpes simplex virus type 2 (HSV-2)
According to the CDC, in most cases, the first herpes outbreak occurs within a few days to a couple of weeks after initial contact. However, in some cases, you can go several weeks between the initial infection and the first outbreak
Symptoms usually go away within 2 to 3 weeks, and even faster if you are treated with medication. Unfortunately, the virus stays in your system for life, and can “flare up” again at a later time. Repeat outbreaks of genital herpes are especially common during the first year after infection.
According to the CDC, the first outbreak is usually the worst. Any recurring outbreaks are usually less severe and shorter. Some patients report minor tingling in the area where they were initially infected prior to recurring herpes flares.
The number of outbreaks an individual has tends to decrease over time, and recurrences in general are less frequent for individuals with a genital HSV-1 infection than for genital HSV-2 infection.
Wednesday, 14 December 2016
What Happens to Your Brain under Anesthsia...
GENERAL ANESTHESIA AND THE HUMAN BRAIN
How going under may impact cognitive function
If you’ve ever had surgery, your anesthesiologist has likely told you to count back from 100. You don’t get too far before you’ve drifted off. Hours later, you wake up from the “reversible coma” often unaware of whatever happened during the surgery. But what happens when the body, specifically the brain, goes through this procedure, and why are we unable to feel pain or remember anything?
ANESTHESIA DOSAGE
In the U.S., 40 million anesthetics are administered to patients every year, yet many questions still surround the drugs and their effects. Anesthesia, as a procedure, is considered successful when a patient has successfully experienced amnesia, analgesia, muscle relaxation, and loss of consciousness. However, going with a dose that’s too low or too high has also caused patients to wake up in the middle of surgery, while others have experienced postoperative cognitive decline.
For surgery, the recommended dose of general anesthesia is at least 1 minimum alveolar concentration (MAC) — the standard measure signifying the concentration of anesthesia in vapor. Fifty percent of people who inhale 1 MAC of anesthesia don’t move in response to a pain stimulus, and studies suggest it takes lower concentrations of anesthetic to induce unconsciousness than it does to prevent movement in response to surgery.
Dosing is contingent on two factors: the patient’s health profile and the anesthetics and sedatives that are used. Anesthesiologists use a combination of drugs, including xenon gas, sevoflurane, propofol, and midazolam to achieve an anesthetic state — they must also be on hand at all times to constantly monitor patients’ vital signs. So far, through research involving functional magnetic resonance imaging (fMRI), researchers have learned that different drugs and doses cause different effects in the brain. Here’s what they do.
YOUR BRAIN ON SEVOFLURANE
Sevoflurane is often used to induce or maintain unconsciousness in patients undergoing surgery, and doses lower than 1 MAC of the inhaled anesthetic agent are enough to affect memory-related regions of the brain. These regions include the primary visual cortex and its association cortex, which translates the information gathered into complex representations.
A 2007 study published in the journal Anesthesia and Analgesia, for example, found that only 0.25 MAC sevoflurane could increase levels of cerebral blood flow (CBF) in the brain’s occipital lobe, where the visual processing centers reside. This increased CBF influences how brain cells try to survive as well as the way they perform their designated tasks, such as thinking, ultimately slowing everything down.
Another study from 2008 arrived at similar results. After administering 0.5 MAC of sevoflurane, researchers saw changes in CBF within the frontal and parietal lobes, which house brain regions responsible for memory and sensory functions. This in turn brings more oxygenated blood to the brain, which researchers speculate results in memory loss. However, so much oxygen can also overflood the region and damage neural tissue.
These findings are consistent with what researchers already know about the effects of general anesthetics. Sevoflurane and other anesthetics trigger a nerve impulse when they make contact with the synapses in the brain. Under normal circumstances, these signals would then be sent from the primary regions to the secondary, and finally to the tertiary regions where multiple types of stimuli are combined and processed. However, when that signal comes from an anesthetic, the anesthetic is believed to build on each synapse it passes throughout this chain, eventually affecting all regions with a larger effect.
YOUR BRAIN ON PROPOFOL AND KETAMINE
The widely used anesthetic propofol (a hypnotic drug) not only causes unconsciousness but amnesia too. Researchers believe propofol binds to GABA receptors, which are involved in controlling sleep and alertness.
A 2011 study published in the European Journal of Anesthesiology suggested that rather than suddenly switching off, consciousness actually fades away. The study found consciousness resides in the connections between multiple parts of the brain, not just one single region, and that an anesthetized brain was first affected in the midbrain where there’s an abundance of GABA receptors. Once propofol binds to these receptors, it mimics and enhances the effects of GABA, thus inhibiting cellular activity. Consciousness fades as the drug spreads outward to different regions of the brain.
Along with propofol, anesthetists often give patients anesthetics with an analgesic effect. While these are sometimes opioid painkillers, other times they’re the drug ketamine. While in lower doses, this drug turns the brain highly active, in higher doses it’ll have the opposite effect. Ketamine is a dissociative anesthetic, which means it doesn’t make patients completely unconscious. Rather, it inhibits their senses, judgement, and coordination for up to 24 hours.
Ketamine doesn’t induce amnesia or forgetfulness, Dr. Theodore Henderson, founder of the Neuro-Laser Foundation and Neuro-Luminance in Denver, Colo., told Medical Daily in an email. He said the drug blocks NMDA receptors, which are critical to learning, memory, locomotion and neural plasticity.
Together these drugs work on patients by sedating them and providing painkilling benefits.
THE DEVELOPING BRAIN ON ANESTHETICS
Children who are exposed to anesthesia only once can be at a higher risk of neurodevelopmental problems and changes in brain structure. A recent review published in the journal Pediatrics found children under 4 years old who received general anesthesia prior to undergoing surgery were more likely to experience problems with language comprehension; have a lower IQ; and exhibit decreased gray matter density in regions toward the back of their brains — specifically in the occipital lobe and cerebellum, which coordinates and regulates muscular activity. The drugs used on these kids, some of whom underwent multiple early-life surgeries, included sevoflurane, isoflurane, and halothane.
Another study from 2012 found children who underwent anesthetic surgeries before age 3 were also twice as likely to develop learning disabilities, including long-term language and reasoning deficits before the age of 10. However, the researchers saw there weren’t any observed differences when it came to behavior, visual tracking, attention, or fine and gross motor function.
In all, these studies highlight the need to look for better methods for administering anesthesia for children — researchers are working on it.
THE AGING BRAIN ON ANESTHESIA
Those who undergo surgery later in life most often do so for health-related issues more often than cosmetic. But with age also comes a longer recovery time. Older patients can take up to six months to recover from anesthesia following a surgery, according to a 2013 study. In part, this recovery takes so long because elderly patients are more likely to experience slight changes in their mental capacity, which may place them at higher risk for dementia — as much as 35 percent higher, the study found. Researchers believe this is because anesthesia causes inflammation to neural tissues. In turn, this increases a person’s chances of developing postoperative cognitive dysfunction (POCD) or precursors to Alzheimer’s disease, such as beta-amyloid plaques.
These findings suggest the elderly could use a lower dose of anesthesia before undergoing surgery. After all, they’re more prone to other health conditions, such as hypertension, diabetes, and heart disease, and might even be taking drugs to treat these conditions. Complications could arise from either of these factors when a person is put under.
THE FUTURE OF ANESTHESIA
Researchers have gotten loads of insight regarding the effects of anesthetics on the brain thanks to fMRI. Yet despite knowing they can reliably put someone to sleep during surgery, without causing pain, they still don’t know every detail regarding how anesthetic drugs work. This compilation of studies suggests the brain undergoes changes in an anesthetic state, and that these drugs — if not used properly — can be harmful to patients. But until further research is completed to map the brain under anesthesia, we won’t know the best approach to dealing with them.
Tuesday, 13 December 2016
Snoring - Identify the cause to find the cure
Forty-five percent of normal adults snore at least occasionally and 25 percent are habitual snorers. Problem snoring is more frequent in males and overweight people and usually worsens with age. Snoring may be an indication of obstructed breathing and should not be taken lightly.
What causes Snoring?
The noisy sounds of snoring occur when there is an obstruction to the free flow of air through the passages at the back of the mouth and nose. This area is the collapsible part of the airway where the tongue and upper throat meet the soft palate and uvula. Snoring occurs when these structures strike each other and vibrate during breathing.
In children, snoring may be a sign of problems with the tonsils and adenoids. A chronically snoring child should be examined by an otolaryngologist, who may recommend a tonsillectomy and adenoidectomy to return the child to full health.
The following conditions can affect the airway and cause snoring:
-Being overweight or out of shape. Fatty tissue and poor muscle tone contribute to snoring. Even if you’re not overweight in general, carrying excess weight just around your neck or throat can cause snoring. Exercising and losing weight can sometimes be all it takes to end your snoring.
-Your mouth anatomy. Having a low, thick soft palate can narrow your airway. People who are overweight may have extra tissues in the back of their throats that may narrow their airways. Likewise, if the triangular piece of tissue hanging from the soft palate (uvula) is elongated, airflow can be obstructed and vibration increased.
-Alcohol consumption. Snoring can also be brought on by consuming too much alcohol before bedtime. Alcohol relaxes throat muscles and decreases your natural defenses against airway obstruction.
-Nasal problems. Chronic nasal congestion or a crooked partition between your nostrils (deviated nasal septum) may contribute to your snoring.
-Sleep deprivation. Not getting enough sleep can lead to further throat relaxation.
Sleep position. Snoring is typically most frequent and loudest when sleeping on the back as gravity's effect on the throat narrows the airway.
-Obstructive sleep apnea. Snoring may also be associated with obstructive sleep apnea. In this serious condition, your throat tissues partially or completely block your airway, preventing you from breathing.
OSA often is characterized by loud snoring followed by periods of silence when breathing stops or nearly stops. Eventually, this reduction or pause in breathing may signal you to wake up, and you may awaken with a loud snort or gasping sound.
You may sleep lightly due to disrupted sleep. This pattern of breathing pauses may be repeated many times during the night.
People with obstructive sleep apnea usually experience periods when breathing slows or stops at least five times during every hour of sleep
People who snore may suffer from:
• Poor muscle tone in the tongue and throat: When muscles are too relaxed, the tongue falls backwards into the airway or the throat muscles draw in from the sides into the airway. Some relaxation is natural during deep sleep, but may become a problem if exacerbated by alcohol or drugs that cause sleepiness
• Excessive bulkiness of throat tissue: Children with large tonsils and adenoids often snore. Overweight people may have excess soft tissue in the neck that can lead to airway narrowing. Cysts or tumors are rare causes of airway narrowing.
• Long soft palate and/or uvula: A long palate narrows the opening from the nose into the throat. The excessive length of the soft palate and/or uvula acts as a noisy flutter valve during relaxed breathing.
• Obstructed nasal airways: A stuffy or blocked nose requires extra effort to pull air through it. This creates an exaggerated vacuum in the throat that pulls together the floppy tissues of the throat, and snoring results. So snoring may only occur during the hay fever season or with a cold or sinus infection. Also, deformities of the nose or nasal septum, such as a deviated septum (a deformity of the wall that separates one nostril from the other) can cause such an obstruction.
HOW you snore reveals WHY you snore
Type of snoring, What it may indicate
Closed-mouth snoring may indicate a problem, with your tongue
Open-mouth snoring, may be related to the tissues in your throat
Snoring when sleeping on your back, Probably mild snoring—improved sleep habits and lifestyle changes may be effective cures
Snoring in all sleep positions, can mean your snoring is more severe and may require a more comprehensive treatment
SELF-HELP FOR SNORERS
Adults who suffer from mild or occasional snoring should try the following self-help remedies:
• Adopt a healthy and athletic lifestyle to develop good muscle tone and lose weight.
• Avoid tranquilizers, sleeping pills, and antihistamines before bedtime.
• Avoid alcohol for at least four hours and heavy meals or snacks for three hours before retiring.
• Establish regular sleeping patterns.
• Sleep on your side rather than your back.
• Elevate the head of your bed four inches.
Source: American Academy of Otolaryngology
Monday, 12 December 2016
The Unexpected effects weed has on your eyes...
A new study published in JAMA Opthamol found that regular cannabis use can delay how visual information is processed in the eye’s retina.
Researchers found that regular pot users experience a slight delay in the functioning of their retinal ganglion cells (RGCs). These cells work to process incoming visual information and are responsible for connecting the retina to the brain, according to an article in Medical XPress. However, researchers cautioned that the study was small, and they're still not sure if the delay is permanent or may recede over time when the user stops smoking pot.
These retinal cells are also partially responsible for transforming light into a series of electrical pulses, called action potentials, in the brain, CNN reported.
Researchers examined 52 participants, 28 of whom were regular marijuana users — meaning they used cannabis at least seven times a week. They found that cannabis smokers experienced a delayed response time in processing visual information when compared to the control group. The pot users "experienced a 10-millisecond delay in the speed with which their RGCs sent key signals to the brain via the optic nerve," Medical Xpress reported.
Following the study, the research team suggested that smokers might be experiencing vision trouble without being consciously aware of it.
"Such an anomaly could be imperceptible for cannabis users," Dr. Vincent Laprevote — lead author of the study and a physician at Pole Hospitalo-Universitaire de Psychiatrie du Grand Nancy in Laxou, France — told CNN. "However, it is important, since it could reflect the changes in the communication between neural cells implied by regular cannabis use."
Many proponents of marijuana claim that it has no lasting effects on the body. Science has proven that this is not true. Marijuana can impact many systems in the body, including the eyes. In fact, marijuana is often touted as a treatment for patients with glaucoma.
How does marijuana impact vision?
Marijuana’s Impact on the Body
There are many known effects on the body when using marijuana. Some of these relate to the eyes while others impact other areas of the body. Studies have found that attention, memory and learning are all impaired by heavy marijuana use, even after stopping the drug for more than 24 hours. Marijuana users also exhibit impaired driving abilities, slower reaction times and difficulty concentrating. Marijuana can also impact perception, making colors appear brighter, etc. When it comes to eyesight marijuana commonly alters peripheral vision.
Marijuana has long been known to have an impact on nervous system communications, according to Medical XPress.
Source: Schwitzer T, Schwan R, Albuisson E. Association Between Regular Cannabis Use and Ganglion Cell Dysfunction. JAMA Ophthalmol. 2016.
WHY YOU SHOULDN'T EAT OR DRINK ANYTHING BEFORE SURGERY
If you’ve ever prepared for an operation involving anesthesia, then you’re probably familiar with the phrase “NPO after midnight.” Nil per os in latin, or nothing by mouth, is a policy that asks patients to refrain from eating or drinking anything in the eight to 12 hours leading up to their operations. Doctors usually have a reason for the advice they give, but many inquisitive patients wonder why they have to starve themselves before going under the knife.
Although general anesthesia is essential to controlling pain by rendering a patient unconscious during a procedure, there are risks involved with this medication that anesthesiologists have worked to reduce. They ban food or drink after midnight to prevent pulmonary aspiration, the inhalation of food, liquids, solids, or vomit into the lungs or airways rather than through the esophagus to the stomach. This can lead to blocked airways and subsequent pneumonia.
For decades, fasting guidelines have been given to anyone preparing for an operation, but more recent evidence has shown this may be an overly cautious practice. In fact, around 50 percent of anesthesiologists say they no longer require NPO after midnight for elective surgery. However, parents are still advised to stop giving their children solid food at midnight the evening before surgery. Clear liquids, such as water, apple juice, sports drinks, Pedialyte, and JELL-O, are safe to drink until four hours before a procedure.
Sunday, 11 December 2016
The New Gene Technology - Can it make perfect humans?
PERFECT HUMANS AND DESIGNER BABIES: HOW CRISPR TECHNOLOGY EDITS GENES IN HUMAN DNA
It seems as though there are few limits when it comes to genetic engineering today, as the notion of editing genes to remove mutations or disorders has become a reality. A new type of genetic engineering, known as CRISPR/Cas system, in particular offers a huge potential in editing genomes with the possibility of removing faulty genes and replacing them with functional ones, rewriting muscular dystrophy genes, or protecting us from tropical diseases like malaria — and much more.
Amazingly, CRISPR/Cas was adopted from an immune system function in bacteria (humans really looked to nature on this one). CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeat, refers to short sections of repeating DNA in bacteria or other microorganisms. These sequences are important for the organism’s immune system function. To understand how CRISPR works, we first have to know how the system works in bacterial immune systems. When a virus invades a bacterium, it replicates its DNA until it completely takes over the cell. But the bacterium has to stop the replication in order to survive. To do that, it must destroy the viral genome, and this is where the CRISPR/Cas system comes in.
Within a bacterium’s CRISPR, there are small parts of the DNA called spacers, which contain information about viruses that have previously attacked. It’s a way of notifying the bacterium’s immune system to attack a virus. But if the virus is new, the viral DNA must first be placed into the CRISPR sequence as a new spacer. Once that’s done, the viral DNA is copied into an RNA molecule — and then Cas enzymes, or CRISPR-associated proteins, come to the rescue. Cas enzymes, particularly Cas9, are the immune system elements that enter the RNA molecule, attack viral DNA, and cut it in half to prevent replication.
Scientists can take this system and apply it to humans and other animals, to adjust genes, remove mutations, or even add completely new ones. It’s a powerful system that has huge implications for the future of genetic engineering, but the question remains whether it will lead to designer babies or the development of “perfect human"
By Lecia Bushak
What skipping meals does to your body...
SKIPPING meals promotes belly fat storage, Increases risk for insulin's resistance
Anyone looking to lose weight knows they have to restrict the amount of calories they consume, but how much and when they restrict those calories can make all the difference. A recent study conducted at Ohio State University has revealed that skipping meals not only leads to abdominal weight gain, but it can also lead to the development of insulin resistance in the liver.
"This does support the notion that small meals throughout the day can be helpful for weight loss, though that may not be practical for many people," Martha Belury, professor of human nutrition at Ohio State University, said in a statement. "But you definitely don't want to skip meals to save calories because it sets your body up for larger fluctuations in insulin and glucose and could be setting you up for more fat gain instead of fat loss."
Belury and her colleagues divided mice into two groups: one group that was put on a restricted diet and a second group that was put on an unlimited diet. Mice from the restricted diet group received half of the calories that were given to the unlimited diet group in the first three days before having additional calories added. Although mice in the restricted diet group initially lost more weight compared to those from the unlimited diet group, they regained that weight as calories were added back into their diet.
By the end of the study, the weight of the restricted diet group was similar to the unlimited diet group. However, restricted diet mice had gained more weight around their midsection. Weight around the midsection of mice was likened to belly fat in humans, which is often associated with insulin resistance and higher risk for type 2 diabetes and heart disease.
"With the mice, this is basically binging and then fasting," Belury exaplined. "People don't necessarily do that over a 24-hour period, but some people do eat just one large meal a day. Under conditions when the liver is not stimulated by insulin, increased glucose output from the liver means the liver isn't responding to signals telling it to shut down glucose production. These mice don't have type 2 diabetes yet, but they're not responding to insulin anymore and that state of insulin resistance is referred to as prediabetes."
As the study continued, mice developed gorging eating habits that caused them to finish their daily amount of food in around four hours and fast for the remaining 20 hours of the day. Gorging and fasting among mice led to a spike and then a severe drop in insulin that causes a variety of metabolic issues. Mice from the restricted diet group often experienced elevations in inflammation and a higher activation of genes that lead to the storage of fatty molecules and plumper fat cells — predominantly in the midsection.
Even though the gorging and fasting mice had about the same body weights as control mice, their adipose depots were heavier,” Belury added. “If you're pumping out more sugar into the blood, adipose is happy to pick up glucose and store it. That makes for a happy fat cell — but it's not the one you want to have. We want to shrink these cells to reduce fat tissue.”
A similar study conducted at the Oregon Research Institute (ORI) found that skipping meals or restricting the number of calories you consume each day can actually make unhealthy food more attractive. When adolescents who willingly curbed their eating habits were shown pictures of unhealthy but appetizing food, brain imaging showed a spike in hyperactivity.
So, no matter the reason, skipping meals is depriving the body of essential nutrients.
Source: The Journal of Nutritional Biochemistry 2015.
Study finds link between Insomnia and Asthma
A new study from researchers at the University of Pittsburgh has found that insomnia is very common in adults with asthma .
The team found that clinically significant insomnia was present in 37 percent of study participants with asthma, according to a recent statement. These results also suggest that adults with the chronic respiratory condition who also have insomnia may be at increased risk for issues such as depression and anxiety .
Patients with asthma commonly say they have some difficulty with sleep, but reported that these issues are not due to asthma symptoms disturbing their slumber. Additionally, researchers found that those with the condition generally had a higher BMI, worse lung function and lower annual household income compared to people without insomnia,
"Our results show that poor sleep may not be solely due to nighttime awakening due to asthma symptoms but may represent comorbid insomnia," said lead author Faith Luyster, PhD, according to the statement. "... comorbid insomnia can significantly impact asthma outcomes including quality of life and healthcare utilization."
The authors said more studies are needed before we can clearly understand the relationship between asthma and insomnia. Going forward,they recommended further research on how cognitive-behavioral therapy might affect the sleep disorder.
Common signs and symptoms of asthma include coughing, wheezing, chest tightness, and shortness of breath. According to the National Heart, Lung, and Blood Institute , proper treatment typically results in fewer, if any, asthma symptoms either during the day or at night.
Source: Luyster FS, Strollo PJ, Holguin F, Castro M, Dunican EM, Fahy J, et al. Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program. CHEST . 2016.
Saturday, 10 December 2016
Low Sperm Count _ What you need to know...
you ejaculate during an orgasm contains fewer
sperm than normal. Your sperm count is considered lower than normal if you have fewer than 15 million sperm per milliliter of semen. Having a low sperm count decreases the odds that one of your sperm will fertilize your partner's egg, resulting in PREGNANCY Nonetheless, many men who have a low sperm count are still able to father a child.
SYMPTOMS:
#1. The main sign of low sperm count is the inability to conceive a child.
#2. Problems with sexual function
— for example, low sex drive or difficulty
maintaining an erection
#3. Decreased facial or body hair
#4. Are unable to conceive a child after a year of
regular
#5. Have pain, discomfort, a lump or swelling in the
testicular area
#6. Have a history of testicle, prostate or sexual
problems
#7. Have had groin, testicle, penis or scrotum
surgery
PREVENTION:
*Don't smoke.
*Limit or abstain from alcohol.
*Steer clear of illegal drugs.
*Keep the weight off.
*Avoid the heat.
*Reduce stress.*Avoid pesticides, heavy metals and other toxins
*Take medications that can boosts your sperm count.
Treatments for low sperm count include:
Surgery. For example, a varicose can often be surgically corrected or an obstructed vas deferens repaired. Prior vasectomies can be reversed. In cases where no sperm are present in the ejaculate, sperm can often be retrieved directly from the testicles or epididymis using sperm retrieval techniques.
Treating infections. Antibiotics can cure an infection of the reproductive tract, but this doesn't always restore fertility.
Treatments for sexual intercourse problems. Medication or counseling can help improve fertility in conditions such as erectile dysfunction or premature ejaculation.
Hormone treatments and medications. Your doctor might recommend hormone replacement or medications in cases where infertility is caused by high or low levels of certain hormones or problems with the way the body uses hormones.
Assisted reproductive technology (ART). ART treatments involve obtaining sperm through normal ejaculation, surgical extraction or from donor individuals, depending on your specific case and wishes. The sperm are then inserted into the female genital tract, or used for in vitro fertilization or intracytoplasmic sperm injection.
BE WARNED - Fake and Real Rice
Rumor has it that the rice we purchase in the stores is fake. There was an evidence found in a country in Asia that fake rice has been produced massively, even though people do not believe in this information. For that reason you need to pay close attention at what you are buying.
China was the first place this fake rice appeared for the first time. Then it appeared in Vietnam and India, i.e. countries where rice is the main meal. However, it can be found in Indonesia and Europe, but it is not present in the USA as of yet. Even brand companies use it. It looks like the real one, thus it is really hard to make a difference. The fake rice makes a lot of stomach issues.
The issue can be solved if you don’t consume the rice at all. There has been information that it contains potatoes and synthetic rest in it, while some say that there are chemicals, too. His is not the case in Malaysia where bigger markets have a serious control of the products, thus it is almost impossible to find it there. However, smaller markets may have it as they do not make this kind of control.
How to make a difference between the real and fake rice?
The best way to see this is by boiling the rice. The fake one will keep its form that it had before boiling which is not the case with real rice. It changes its form after it boils. Moreover, you may feel the plastic on your hands and it releases a weird smell..
Friday, 9 December 2016
Healthiest Food on Earth
1. Berries
All berries are low in sugar and high in fiber. Blueberries have been shown to increase memory in lab studies, and raspberries and strawberries are loaded with ellagic acid, a powerful antioxidant that seems to have some anti-cancer properties, according to the American Cancer Society.
2. Beans
Beans are extremely high in fiber, which helps to control weight, prevent or manage diabetes and blood sugar, and may help prevent colon cancer and protect against heart disease. The National Institute of Medicine recommends 25-38 grams of fiber a day. The average American gets only 4-11 grams. One cup of beans provides 11-17 grams.
3. Nuts
Some of the largest and most important long-term studies of diet and health have shown that eating nuts several times a week is consistent with a risk of heart attack and heart disease that is 30%-50% lower than the general population. Just one ounce of nuts-almonds, macadamia, Brazil , walnuts, pecans-eaten three to five times a week seems to be the magic number.
4. Wild Salmon
Fish is the ultimate anti-aging food. Cold-water fatty fish like wild salmon, sardines, mackerel and herring contain omega-3 fats that protect the brain and the heart, improve mood, and lower blood pressure and triglycerides.
5. Raw Milk
Raw, organic milk nearly always comes from grass-fed cows and contains high levels of cancer-fighting CLA (conjugated linolenic acid) as well as a rich assortment of vitamins, minerals and beneficial bacteria (like Lactobacillus acidophilus)
6. Grass-Fed
Meat Meat from grass-fed cows has a much different fat profile than ordinary supermarket meat: high in omega-3s, lower in potentially harmful omega-6s and loaded with CLA, a kind of fat known for its anti-cancer activity. A superb source of protein and vitamin B12, it's also missing the antibiotics, steroids and hormones found in the meat that comes from feedlot farms.
7. Eggs
Considered by many to be nature's most perfect food, the egg is high in protein and relatively low in calories. The yolk contains choline, one of the most important nutrients for the brain, as well as lutein and xeazanthin, two critical nutrients for eye health. Brassica Vegetables Cabbage, Brussels sprouts, broccoli and kale all contain plant compounds called indoles that help reduce the risk of cancer. In addition to a stunning range of vitamins and minerals, they also contain sulforaphane, an important plant chemical that helps the body detoxify health-damaging chemicals.
8. Apples
Not only do they keep the doctor away, they also appear to do the same for lung cancer, diabetes and asthma. An apple contains five grams of fiber and a rich blend of nutrients including the bone-building vitamin K and the anti-inflammatory nutrient quercetin. And there's no better way to control your appetite than an apple eaten about half an hour before a big meal.
9. Onions and Garlic
In an impressive number of published studies, the consumption of onions and garlic has demonstrated protective effects against stomach, prostate and esophageal cancer. Along with broccoli, tea and apples, onions and garlic are among a select group of foods found to reduce mortality from heart disease by 20%.
10. Pomegranate Juice
Called "a natural Viagra" by researchers at Tel Aviv University , pomegranate juice is loaded with antioxidants. Studies show it can reduce blood pressure and plaque in the arteries. New research indicates it also slows the progression of tumors.. Four to eight ounces a day is highly recommended.
11. Green Tea
Though all teas are great for yoju, green tea has a unique profile of plant chemicals that have anti-cancer activity. It's now fairly established that green tea may help prevent the following types of cancers in humans: bladder, colon, esophagus, pancreas, rectum and stomach. If that's not enough, it also appears to help with weight control.
Thursday, 8 December 2016
Scientist discovers the chemistry of Halitosis
Fortunately, scientists are working on what exactly causes halitosis, as well as which chemicals cause the odors of special kinds of halitosis.
Let's start with coffee. A recent Harlequin Survey found that 49 percent of men and 62 percent of women think that oral odor caused by a cup of java is the number-one turnoff, as reported by the Toronto Sun.
Where does the odor of coffee breath come from? In essence, nearly any food can cause bad breath simply by giving oral microbes something to eat. These bacterial colonies are semi-permanent fixtures in the mouth, usually only disappearing if new, more productive microorganisms are introduced to the palate via oral care probiotic products.
However, coffee breath has a specific scent. This comes from several organic compounds found in the the beverage. One is called 3-mercapto-3-methylbutylformate (3M3M), according to the Coffee Research Institute (CRI). It is a molecule closely related to methyl mercaptan. If you've ever smelled rotten cabbage, you know what methyl mercaptan smells like.
Coffee contains lots of 3M3M, typically about 0.3 milligrams per liter of the drink, according to the CRI. With this compound coating your tongue and teeth, you're almost guaranteed to have halitosis. The Good Scents Company, which lists the odor properties of the molecule as "catty" and "sweaty," puts it succinctly: "Not for fragrance use."
Garlic breath comes from another methyl-group compound, one called allyl methyl sulfide (AMS). Unlike 3M3M, which is usually described through analogies to other smelly things, AMS smells like one thing only - garlic.
Eat some garlic, and your mouth will almost assuredly reek of AMS. Rinsing with a specialty breath freshener is one effective way to alleviate this odor before it becomes problematic.
Finally, researchers have recently looked into the chemical content of fish, and fish breath. To do so, a group of scientists from Spain and India prepared samples of anchovy sauce and then analyzed them using miscellar liquid chromatography, a technique that reveals a sample's chemical contents.
The group found that anchovy sauce contains between 0.5 and 2 parts per million (ppm) of putrescine, an aromatic molecule that gives rotting meat its distinctive aroma. They noted that the 2 ppm sample had probably spoiled. Fish breath, as well as breath scented with other meats or cheese, is likely to be loaded with putrescine.
Researchers have identified around 150 different molecules in human breath, many of which offend the human nose. Here are what some of the more malodorous compounds smell like.
Rotten eggs
Hydrogen sulfide (H2 S)
Rotten cabbage
Methyl mercaptan (CH 3 SH)
Garlic
Allyl mercaptan (C 3 H6 S)
Allyl methyl sulfide (C 4 H8 S)
Fish
Dimethylamine (C 2 H7 N)
Computer Vision Syndrome - The 20-20-20 Rule
Research is showing a rise in the detection of visual problems because of the number of hours spent in front of a laptops, computers, smartphones, gaming systems and television. This can put a lot of strain on our eyes and cause eye fatigue. When using your screens give your eyes a break. Uncorrected hyperopia, myopia ,astigmatism and wearing multifocals can all make computer use less comfortable and efficient. Depending on your condition, your eyes could be exerting extra focusing effort or be forced to work harder to maintain a clear image when viewing the screen. Even people with perfect vision may experience symptoms such as blurred vision, eyestrain and headaches with improper computer use.
To ensure comfortable and efficient computing, Use the 20-20-20 rule.
-Every 20 minutes take a 20 second break and focus your eyes on something at least 20 feet away (the water cooler, possibly?). This will give your eyes a much-needed break and reduce some of the symptoms mentioned earlier.
-Position your screen about an arm’s length from your eyes and 20 degrees below eye level.
-Set colour and contrast tones to suit your eyes and match the brightness of your screen with your surroundings.
-Minimize reflected glare on your screen by using dimmer switches on lights and a protective anti-glare screen cover. Also consider positioning your screen so that it sits perpendicular to windows and other bright light sources. If you are having trouble locating the source of the glare, turn off your monitor to reveal a darkened screen and tilt/swivel your monitor until the reflection disappears.
-Keep your screen free of fingerprints and dust , as both can reduce visual clarity.
-Remember to blink! Did you know that on average we blink 12 times per minute, but when we’re on the computer, we only blink five times per minute? That can add up to dry eyes. Relieve the discomfort by using artificial teardrops or gels and remembering to blink. Consult your eye doctor (ophthalmologist or optometrist ) to determine which eye drops are best to relieve your dry eyes.
-Ask for anti-reflective coatings on the lenses of your glasses, which can be applied at the time of manufacturing, which allow for more comfortable viewing of screens, fluorescent and LED lights. Your eye doctor will talk to you about eyewear designed specifically for computer use.
HIV - Return of a Pandemic
The spread of the human immunodeficiency virus, HIV, is not declining; rather it is on the rise, the major reason being that those living with the virus are not ready to disclose their status for fear of stigma, and are therefore bearing in their strides, and endangering unsuspecting member of the public. Omolara Akintoye reports that achieving an HIV/AIDS free generation requires collective efforts
I could not understand the look on their faces. Time after time, each of them would look at my medical reports and request to see the next person. The one would whisper, ‘Have you told her;’ and the other would say ‘no.’ At last, one of them took the letter to the doctor, who called me in and told me the damning news. ‘You are HIV positive.’”
That was how Shola Umar, then a teenager and an indigene of Lagos, discovered his HIV status 14 years ago in 2002. As if that was not devastating enough, he was sent out of the house by his mum, the moment he broke the news to her. Even the nurses and doctors, who should know better, joined in the stigmatisation. Those were the days when the HIV story was still shrouded in lots of mystery and heavily dreaded; but one still expected succour from such informed quarters.
It all began when he discovered that he was always falling sick. Umar lamented that he would have died because those that he expected support from, especially his mother, deserted him. “My mum said if it is HIV, then it is from my father; so she sent me out of her house. But in spite of all the turbulence, I resolved to live above the challenges and stigma.” He said.
Umar was however not totally alone. His maternal grandfather, who is a medical doctor, encouraged him to be strong. “At a point, my grandfather inquired what I wanted to do for a living; I told him I wanted to be a health worker on HIV issues.”
And that was how he began his advocacy work. He explained that he has been doing advocacy work ever since; moving from one area to the other to sensitise people, especially in the suburbs of Lagos.
“We went to different places in Lagos, especially where those commercial sex workers reside, to sensitise, as well as screen people, so they could know their status.”
Umar has done advocacy work with the Lagos University Teaching Hospital, LUTH and is presently working with the General Hospital, Lagos Island, where he has joined a support group.
Olaoye, who is based in Oyo State, is another person living with HIV. He said, “I’ve been living with this virus since 1998 and here I am, still healthy. Even my wife and our last child have this virus. We’re all on drugs and no one will ever know that we are infected.”
Olaoye however advised people living with the virus to abstain from alcohol and smoking of India hemp and cigarette, as this could be damaging to their immune system. He also urged people to check their status on time, so they could immediately start treatment; in case they’re positive. He enjoined them to also go for counselling, to manage the psychological effect of the discovery.
Olaoye also urged the government to bring in experts in the field, to further notch up the standard of care and treatment in the country to meet international standards.
In the vein, Amina (not real name) discovered her HIV status when she was age 15, but was lucky to get the right counseling and is today happily married to a husband who is also positive. The greater news however, is that they both have a kid, who is negative.
Different stories abound about People Living with HIV/AIDS. The saddest part however is the recent unprecedented rise in the statistics of infected people in certain parts of the country. For instance, the Lagos State government recently revealed that a whopping 9, 572 people tested positive to the virus in the state between January and June this year alone. This is especially scary, as it seems the people have largely let down their guards. It is for this reason that the theme of this year’s World AIDS Day commemoration, Hands Up for HIV Prevention, becomes highly instructive.
Umar however blames the reason for this unhealthy rise partly on the problem of stigmatisation. He said, “Though it (stigmatisation) has reduced as a result of sensitisation and awareness, it is still on and is preventing many people who test positive from coming forward to declare their status. This, no doubt, is making the virus to be on the rise, rather than decline.”
He disclosed that people come into the hospital on a daily basis to know their status, with many testing positive on a daily basis.
In an interview with the Acting Executive Secretary of the Nigerian Business Coalition Against AIDS (NIBUCCA), Gbenga Adeolu-Alabi, he spoke extensively about what the organisation has been doing in the last 13 years to curb the spread of the virus in the workplace. NIBUCCA, he said, is the business community’s response to the HIV/AIDS challenge in Nigeria and was established in 2003 during the administration of President Olusegun Obasanjo, when the HIV prevalence was high.
He pointed out that “those that are actually affected by HIV/AIDS are the working class between 19-50 years of age. That was what gave birth to Nigeria Business Coalition Against AIDS (NIBUCCA). That is why government thought it wise to establish NIBUCCA to address HIV/AIDS in the workplace.”
So far, Adeolu-Alabi said the experience as Executive Secretary of the body has been interesting and challenging. “Interesting in the sense that all the organisations are not on the same page,” he said.
Explaining the challenges, Adeolu-Alabi said he has been able to interact with three sets of people in the course of his work namely, the unaffected, the affected and the infected. To the unaffected, he said NIBUCCA provides necessary information. “Most Nigerians who are unaffected believe HIV/AIDS is not real, so we put together programmes to enable them see that the pandemic is real.”
For the infected (People Living With the Virus), he said NIBUCCA encourages them to change their behaviour. “We introduce human face to the virus, as well as preach hope to them. We also provide job opportunities for them. NIBUCCA takes care of wives and children of those with the virus, whom we call Orphan and Vulnerable Children (OVC). Failure to do this will encourage stigma, which will no doubt aid the spread the virus the more.”
Speaking about stigma, Adeolu-Alabi said though it has reduced but it is still there. “As a result of stigma and discrimination, PLWHAs (People Living With HIV/AIDS) don’t want to declare their status. In Africa, our health challenges are shrouded in secrecy because of stigma and discrimination.”
Like Umar, Adeolu-Alabi is of the opinion that stigmatisation aids the spread of the virus. “Once you are infected, UN Initiative says you are expected to commence treatment, but once you get to the health facility and people get to know, stigma sets in, making such persons to run away from accessing treatment.”
He said failure to access treatment automatically increases the infection, as the viral load keeps increasing; while accessing treatment prevents new infections, as it suppresses the virus and one can have sex once it gets to an undetectable level.
Another major issue, Adeolu-Alabi said, is funds. He revealed that many years back, Nigeria was getting funds from donors such as Global Fund, USAID, among others, which were used to institutionalise HIV/AIDS programmes, especially in the workplaces. But now that the fund is no more forthcoming, most of the SMEs are struggling.
“To compound the economic issues, Nigeria is now in recession and experiencing economic meltdown, which is called ‘donor fatigue’. Most PLWHAs are no more enjoying easy access to treatment, as most of the ART (anti-retroviral therapy) drugs from donors are no more there and government is not able to provide enough resources to sustain those on treatment. “The only way out,” he pointed out, “is for us to look inward and source for means of sustaining the programme by increasing the tempo of our activities.
“Also, there is need for the three arms of government to make available a substantial amount of resources to be used to address HIV and AIDS.”
The Lagos State government for one is not resting on its oars, especially with the alarming statistics of nearly ten thousand new cases in the first half of 2016 alone. Aside risky sexual behaviours, there are so many other activities people engage in that may promote the spread of HIV. This includes harmful traditional practices such as female genital mutilation. Three types of female circumcision occur in Africa.
According to Oyefunsho Orenuga, a medical expert with the Lagos State government, the most extreme, termed infibulations or pharaonic circumcision, involves partial closure of the vaginal orifice after excision of varying amount of tissue from the vulva. In its extreme form, all of the mons veneris, labia majora and minora, and clitoris are removed and the involved areas closed by means of sutures or thorns. After the operation, the thighs are strapped together for 4-8 weeks, with complete occlusion of the insertion of a matchstick or other wooden object.
A more moderate form of female circumcision is excision, which involves the removal of the clitoris and part of the labia minora. The mildest form, sunna circumcision, is circumferential excision of the clitoral prepuce.
Another practice, that involves female genital mutilation, is making “gishiri cuts”, which are incisions on the vaginal wall, and presumably serve the same purpose as female circumcision.
“Indeed, most of these cuts are done with tools or instruments that are not sterilised, more so, when those involved in this cultural practice, are not informed about HIV and its transmission. These instruments are thus used repeatedly on numerous girls, thereby increasing the risk of blood-transmitted diseases, including HIV/AIDS. Thus, in a society where information and education on the use of sterilised tools or instruments seem inadequate, the resultant effect is usually an increase in transmission of diseases, such as tetanus, HIV and Ebola virus. This is so because female circumcision has been postulated to increase the likelihood of AIDS transmission via increased exposure to blood in the vaginal cana,” she said.
Another harmful practice, which can also aid the transmission of HIV/AIDS, is the tattoo craze, which Nigerians, seem to have caught. Among those who have heard about HIV/AIDS, most (62.7% of the men and 37.3% of the women) believe that HIV/AIDS could be transmitted through the tattoo incision. But despite this, The Nation gathered that most people are still willing to adorn the tattoos and allow their wards wear them.
In tandem with the foregoing facts, Mrs. Orenuga is of the opinion that practices involving the use of shared instruments (injection of medicines, ritual scarification, group circumcision, genital tattooing, oral tattooing, other body tattooing, tribal markings and shaving of body hair with unsterilised blades) lead to HIV/AIDS transmission.
Similarly, almost all (97.8%) of the women said they like their tattoos. But the question is how safe are the instruments being used for the process?
We’re committed to eradicating HIV by 2030 LSACA boss Speaking on its efforts to curb the HIV spread, the Chief Executive Officer, Lagos State AIDS Control Agency, LSACA, Dr. Oluseyi Temowo said the agency has mobilised its HCT trucks to all the nooks and crannies of the state to conduct free HIV Counselling and Testing. This, he said, would enable every Lagos resident to be aware of their health status.